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1. The primary active ingredient in "red peppers" is a compound called capsaicin. In mammalian cells, it interacts with a type of receptor class called the vanilloid receptors and almost exclusively causes release of a neurotransmitter called "Substance P".
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Here's a story Dave Stark told me: Once he and another guy drove over Murphy Dome to do some fishing on the lower Chatanika. On the west side of the dome, the road drops down into a permafrost bog. That's where they got balled up in the mud on that one-lane road too skinny to turn around in.
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